4,4'-Dimethoxytrityl kloridendi gulu lamphamvu la nucleoside ndi nucleotide lomwe limateteza ndi kuchotsa wothandizira.
Mawu ofanana:DMT-Cl
Nambala ya CAS:40615-36-9
Katundu
Chemical Formula
Kulemera kwa Maselo
Kutentha Kosungirako
Melting Point
Chiyero
Kunja
C21H19ClO2
338.82 g / mol
2 ~ 8℃
120-125 ℃
≥98%
Mtundu wa Pinki
Monga zigawo zofunika za maunyolo a nucleic acid, ma nucleosides ndi nucleotides amagwira ntchito yofunika kwambiri pakufalitsa zambiri zamtundu.Komabe, chifukwa cha reactivity yawo yamankhwala komanso kuwonongeka kosavuta, ma nucleosides ndi ma nucleotide amafunikira ma reagents apadera kuti awateteze panthawi ya kaphatikizidwe.DMTCl4' Dimethoxytrityl (DMTCl) ndi gulu lothandiza kwambiri lomwe limateteza ndi kuchotsa zinthu zomwe zasintha kwambiri chitetezo cha nucleosides ndi nucleotides panthawi ya kaphatikizidwe.
DMTCl ndi hydroxyl kuteteza wothandizila kuti kusankha amachitira ndi hydroxyl magulu nucleosides ndi nucleotides pa kaphatikizidwe kupanga kanthawi kuteteza gulu kuti amaletsa nucleosides ndi nucleotides kuchita ndi mankhwala ena.Gulu loteteza kwakanthawili limachotsedwa mosavuta pambuyo pa kaphatikizidwe, ndikusiya ma nucleosides oyera kapena ma nucleotides.
Chifukwa cha reactivity yake yabwino komanso kusankha,DMTClchimagwiritsidwa ntchito ngati gulu kuteteza ndi kuchotsa wothandizira mu synthesis wa DNA, RNA ndi zina nucleic zidulo.Ndizothandiza makamaka popanga oligonucleotide pomwe kuwongolera kulondola kwa ma nucleotide ndikutsatizana kumafunikira.
Kuphatikiza pa kugwira ntchito ngati gulu loteteza ndi kuchotseratu, DMTCl ndi chitetezo champhamvu cha hydroxyl cha nucleosides ndi nucleotides.Imateteza magulu a hydroxyl a nucleosides ndi ma nucleotides ku okosijeni, kuchepetsa, ndi zina zomwe zingawawononge panthawi ya kaphatikizidwe.
Powombetsa mkota,DMTCl4 4' dimethoxytritylndi chida chofunikira pakupanga ma nucleosides ndi ma nucleotides.Reactivity yake yabwino kwambiri, kusankha ndi kusinthasintha kumapangitsa kukhala gulu loyenera kuteteza ndi kuchotsa wothandizira ndi hydroxyl kuteteza DNA, RNA ndi nucleic acid synthesis.Ngati mukufuna chitetezo chapamwamba komanso chodalirika cha ma nucleosides ndi ma nucleotide panthawi ya kaphatikizidwe, musayang'anenso DMTCl.
Nthawi yotumiza: Jun-08-2023